To cite: Mease PJ, Deodhar AA, van der Heijde D, et al. arthritisAnnals of the Rheumatic Diseases. doi: 10.1136/annrheumdis-2021-221664.
Read the full article here: http://dx.doi.org/10.1136/annrheumdis-2021-221664
Objective: To evaluate the efficacy and safety of an oral selective tyrosine kinase 2 (TYK2) inhibitor, deucravacitinib, in patients with active psoriatic arthritis (PsA).
Conclusions: Treatment with the selective TYK2 inhibitor deucravacitinib was well tolerated and resulted in greater improvements than placebo in ACR-20, multiplicity-controlled secondary endpoints and other exploratory efficacy measures in patients with PsA. Larger trials over longer periods of time with deucravacitinib are warranted to confirm its safety profile and benefits in PsA.
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